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The composition of the gut microbiome is now thought to influence the pathology of mood disorders including schizophrenia and BD, via the microbiome–gut–brain axis
Many of the different symptoms and behaviours typical of bipolar disorder can be modelled in animal behaviour, such as in rodents.
Patients sometimes feel marginalized or stereotyped due to their diagnosis at some point in their lives
Global prevalence of bipolar spectrum disorders
Racial disparities in access to, or provision of, healthcare may contribute to increased morbidity and mortality rates amongst individuals with serious mental illnesses.
The DSM-5-TR acknowledges subthreshold bipolar conditions, reducing the number of individuals formerly categorized as ‘not otherwise specified’.
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