Childhood maltreatment – physical, sexual, or emotional trauma – is increasingly being recognized as a critical factor in psychiatric diagnoses, including depression1,2. People who have experienced childhood trauma typically develop psychiatric disorders earlier than those who have not experienced trauma, and can experience more severe disease and poorer treatment outcomes1.

HAM-D=Hamilton Depression Rating Scale; iSPOT-D=International Study to Predict Optimized Treatment for Depression; MDD=major depressive disorder; SNRI=serotonin–noradrenaline reuptake inhibitor; SSRI=selective serotonin reuptake inhibitor

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